 |


Abeliovich
D, Kaduri L, Lerer I, et al. The founder mutations
185delAG and 5382insC in BRCA1 and 6174delT
in BRCA2 appear in 60% of ovarian cancer
and 30% of early-onset breast cancer patients among Ashkenazi women.
Am J Hum Genet. 1997;60:505-514.

Armstrong
K, et al. Assessing risk of breast cancer. N
Engl J Med. 2000;342:564-71.

Bell
DA, Scully RE, et al. Early de novo ovarian carcinoma:
a study of fourteen cases. Cancer. 1994;73:1859-1864.

Beller
U, Hulle D, Catane R, et al. High frequency of BRCA1
and BRCA2 germline mutations in Ashkenazi
Jewish patients, regardless of family history. Gynecol
Oncol. 1997;67:123-126.

Berchuck
A, Cirisano F, Lancaster JM, et al. Role of BRCA1
mutation screening in the management of familial ovarian cancer.
Am J Obstet Gynecol. 1996;175:738-746.

Bernhart
B. Evaluation of nurses as counselors, Evaluation
of Nurses & Genetic Counselors as Providers of Education About
Breast Cancer Susceptibility Testing. Oncol Nurs
Forum. 27:33-39.

Billings
PR, Kohn MA, de Cuevas M, et al. Discrimination as
a consequence of genetic testing. Am J Hum Genet.
1992;50:476-482.

The
Breast Linkage Consortium. Risks in BRCA2
mutation carriers. JNCI. 1999;91:1310-6.

*Burke
W, Daly M, Garber J, et al. Recommendations for follow-up
care of individuals with an inherited predisposition to cancer.
II. BRCA1 and BRCA2.
Cancer Genetics Studies Consortium. JAMA.
1997;277:997-1003.

The
Cancer and Steroid Hormone Study of the Centers for Disease Control
and the National Institute of Child Health and Human Development.
The reduction in risk of ovarian cancer associated with oral-contraceptive
use. N Engl J Med. 1987;316:650-655.

American
Cancer Society. Cancer Facts &
Figures 1997. Available at: http://www.cancer.org/docroot/stt/stt_0.asp.

From
Cause to Cure, New York Times.
10/10/99

Claus
EB, Schildkraut JM, Thompson WD, et al. The genetic
attributable risk of breast and ovarian cancer. Cancer.
1996;77:2318-2324.

Colditz
GA, Egan KM, Stampfer MJ. Hormone replacement therapy
and risk of breast cancer: results from epidemiological studies.
Am J Obstet Gynecol. 1993;168:1473-1480.

Colditz
GA, Hankinson SE, Hunter DJ, et al. The use of estrogens
and progestins and the risk of breast cancer in postmenopausal women.
N Engl J Med. 1995;332:1589-1593.

Couch
FJ, et al. BRCA2 germline
mutations in male breast cancer cases and breast cancer families.
Nat Genet 1996;13:123-125.

Couch
FJ, DeShano ML, Blackwood MA, et al. BRCA1
mutations in women attending clinics that evaluate the risk of breast
cancer. N Engl J Med. 1997;336:1409-1415.

Couch
FJ, Farid LM, DeShano ML, et al. BRCA2
germline mutations in male breast cancer cases and breast cancer
families. Nature Genetics. 1996;13:123-125.

*Cummings
S, Olopade O. Predisposition testing for inherited
breast cancer. Oncology. 1998:81227-1242.

Early
Breast Cancer Trialists' Collaborative Group. Systemic
treatment of early breast cancer by hormonal, cytotoxic, or immune
therapy. 133 randomized trials involving 31,000 recurrences and
24,000 deaths among 75,000 women. Lancet.
1992;339:1-15.

Easton
DF, Bishop DT, Ford D, et al. Genetic linkage analysis
in familial breast and ovarian cancer: results from 214 families.
Am J Hum Genet. 1993;52:678-701.

Easton
DF, Ford D, Bishop T, et al. Breast and ovarian cancer
incidence in BRCA1-mutation carriers.
Am J Hum Genet. 1995;56:265-271.

Easton,
DF, Steele L, Fields P, et al. Cancer risks in two
large breast cancer families linked to BRCA2
on chromosome 13q12-13. Am J Hum Genet.
1997;61:120-128.

Fearon
ER. Human cancer syndromes: clues to the origin and
nature of cancer. Science. 1997;278:1043-1050.

Fisher
B, Constantino JP, Wickerham L, et al. Tamoxifen for
prevention of breast cancer: Report of the National Surgical Adjuvant
Breast and Bowel Project P-1 study. JNCI.
1998;90:18:1371-1388.

FitzGerald
MG, MacDonald DJ, Krainer M, et al. Germ-line BRCA1
mutations in Jewish and non-Jewish women with early-onset breast
cancer. N Engl J Med. 1996;334:143-149.

Ford
D, Easton DF, Bishop DT, et al. Risks of cancer in
BRCA1-mutation carriers. Lancet.
1994;343:692-695.

Ford
D, Easton DF, Stratton M, et al. Genetic heterogeneity
and penetrance analysis of the BRCA1 and
BRCA2 genes in breast cancer families.
Am J Hum Genet. 1998;62:676-689.

Frank
TS, Manley SA, Olopade OI, et al. Sequence analysis
of BRCA1 and BRCA2:
correlation of mutations with family history and ovarian cancer
risk. J Clin Oncol. 1998;6:2417-2425.

*Frank
TS. Hereditary risk of breast and ovarian carcinoma:
the role of the oncologist. The Oncologist.
1998;3:403-412.

Frank
TS. Risk for ovarian cancer: identifying women with
inherited risk of ovarian cancer: who and why? Contemporary
OB/GYN, December, 1998.

Frank
TS, Skolnick M. Pandora or Prometheus? Commentary:
testing for hereditary cancer risk. J Clin Endo
Metabol. 1999;84:1882-5.

Garber
J. Case Study: A 40 year-old Woman with a Strong Family
History of Breast Cancer. JAMA. 1999;282:1953-60.

Gail
MH, Brinton LA, Byar DP, et al. Projecting individualized
probabilities of developing breast cancer for white females who
are being examined annually. J Natl Cancer Inst.
1989;81:1879-1886.

Geller
G, Bernhardt BA, Doksum T, et al. Decision-making
about breast cancer susceptibility testing: how similar are the
attitudes of physicians, nurse practitioners, and at-risk women?
J Clin Oncol. 1998;16:2868-2876.

Hall
M, Rich S. Laws Restricting Health Insurers' Use of
Genetic Information: Impact on Genetic Discrimination. Am
J Hum Genet. 2000;66:293-307.

Hall
JM, Lee MK, Newman B, et al. Linkage of early-onset
familial breast cancer to chromosome 17q21. Science.
1990;250:1684-1689.

Hammond
CB. Menopause and hormonal replacement therapy: an
overview. Obstet Gynecol. 1996;87:2S-15S.

Hartmann
L, Jenkins R, Schaid D, et al. Prophylactic mastectomy:
preliminary retrospective cohort analysis. Am
Assoc Cancer Research. 1997;38. Abstract No.1123.

Hartmann
L, Schaid D, Woods J, et al. Efficacy of bilateral
prophylactic mastectomy in women with a family history of breast
cancer. N Engl J Med. 1999;340:77-84.

*Huelsman
K, Huppert J, Fiorica J. Screening your patients for
inherited breast and ovarian cancer: how to collect family history
data. Contemporary OB/GYN. 1998;46:107-131.

Johannsson
OT, Ranstam J, Borg A, Olsson H. Survival of BRCA1
breast and ovarian cancer patients: a population-based study from
southern Sweden. J Clin Oncol. 1998;16:397-404.

Lea,
DH. Genetics in Clinical Practice
New Directions for Nursing and Health Care. Jones and Bartlett
Publishers 1998;ISBN: 0-7637-0542-X.

Learman
C. Psychological effects of testing: what you don't
know can hurt you: adverse psychological effects in members of BRCA1-linked
and BRCA2-linked families who decline
genetic testing. J Clin Oncol. 1998;16(5).

Learman
C, Narod S, Schulman K, et al. BRCA1
testing in families with hereditary breast-ovarian cancer: a prospective
study of patient decision-making and outcomes. JAMA.
1996;275:1885-1892.

Malone
K. BRCA Mutations in Young Breast CA Cases: Frequency
of BRCA1/BRCA2 mutations in a population-based
sample of young breast carcinoma cases. American
Cancer Society, 3/15/00, Vol. 88, No 6.

Malone
KE, Daling JR, Thompson JD, O'Brien CA, Francisco LV, Ostrander
EA. BRCA1 mutations and
breast cancer in the general population: analyses in women before
age 35 years and in women before age 45 years with first-degree
family history. JAMA. 1998;279:922-929.

Miki
Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate
for the breast and ovarian cancer susceptibility gene BRCA1.
Science. 1994;266:66-71.

Milner
J, Ponder B, Hughes-Davies L, et al. Transcriptional
activation functions in BRCA2. Nature.
1997;386:772-773.

Monteiro
AN, August A, Hanafusa H. Evidence for a transcriptional
activation function of BRCA1 C-terminal
region. Pro Nat Acad Sci U S A. 1996;93:13595-13599.

NCI
Surveillance, Epidemiology, and End Results Program.
1995.
 
NIH
Consensus Development Panel on Ovarian Cancer: ovarian cancer, screening,
treatment, and follow-up. JAMA.
1995;273:491-497.

Narod
SA, Risch H, Moslehi R, et al. Oral contraceptives
and the risk of hereditary ovarian cancer. N
Engl J Med. 1998;339:424-428.

Oddoux
C, Streuwing JP, Calyton CM, et al: The carrier frequency
of the BRCA2 617delT mutation among Ashkenazi
Jewish individuals is approximately 1%. Nat Genet.
1996;14:188-190.

Offit
K. Clinical Cancer Genetics Risk
Counseling and Management. Wiley-Liss Publishers. 1998;ISBN:
0-471-14655-2.

Parmigiani
G, Berry DA, Aguilar O. Determining carrier probabilities
for breast cancer-susceptibility genes BRCA1
and BRCA2. Am J Hum
Genet. 1998;62:145-158.

Petrij-Bosch
A, Peelen T, van Vliet M, et al. BRCA1
genomic deletions are major founder mutations in Dutch breast cancer
patients. Nat Genet. 1997;17:341-345.

Piver
MS, Baker TR, Jishi MF, et al. Familial ovarian cancer:
a report of 658 families from the Gilda Radner Familial Ovarian
Cancer Registry 1981-1991. Cancer. 1993;71:582-588.

Piver
MS, Jishi MF, Tsukada Y, et al. Primary peritoneal
cancer after prophylactic oophorectomy in women with a family history
of ovarian cancer. Cancer. 1993;71:2751-5.

Ponder
B. Genetic testing for cancer risk. Science.
1997;278:1050-1054.

Prouser
N: Patient case report: genetic susceptibility testing for breast
and ovarian cancer: a patient's perspective. J
Genet Counsel. 2000;9:153-9.

Rajan
JV, Wang M, Marquis ST, Chodosh LA. BRCA2
is coordinately regulated with BRCA1 during
proliferation and differentiation in mammary epithelial cells. Pro
Nat Acad Sci U S A. 1996;93:13078-13083.

Rebbeck
T, et al. Breast cancer risk after bilateral prophylactic
oophorectomy in BRCA1 mutation carriers.
JNCI. 1999;91:1475-1479.

Roa
BB, Boyd AA, Volcik K, et al. Ashkenazi Jewish population
frequencies for common mutations in BRCA1
and BRCA2. Nat Genet.
1996;14:185-187.

Robson
M, Gilewski T, Haas B, et al. BRCA-associated breast
cancer in young women. J Clin Oncol. 1998;16:1642-1649.

Schneider
KA. Counseling About Cancer: Strategies for Genetic
Counselors.1994. Available from the Division of Cancer Epidemiology
and Control, Dana-Faber Cancer Institute.

Schrag
D, Kuntz KM, Garber JE, et al. Decision analysis-effects
of prophylactic mastectomy and oophorectomy on life expectancy among
women with BRCA1 and BRCA2
mutations. N Engl J Med. 1997;336:1465.

Schrag
D. Life expectancy gains from cancer prevention strategies
for women with breast cancer and BRCA1
or BRCA2 mutations. JAMA.
2000;283:617-24.

Scully
R, Chen J, Plug A, et al. Association of BRCA1
with Rad51 in mitotic and meiotic cells. Cell.
1997;88:265-275.

SEER
data. Science. 1993;259:618.

Sharan
SK, Morimatsu M, Albrecht U, et al. Embryonic lethality
and radiation hypersensitivity mediated by Rad51 in mice lacking
BRCA2. Nature.
1997;386:804-810.

Shattuck-Eidens
D, Oliphant A, McClure M, et al. BRCA1
sequence analysis in women at high risk for susceptibility mutations:
risk factor analysis and implications for genetic testing. JAMA.
1997;278:1242-1250.

Shepard,
et al. Testing for genetic susceptibility to ovarian
and breast cancer. Contemporary OB/GYN,
March 1998.

Statement
of the American Society of Clinical Oncology. Genetic
testing for cancer susceptibility. J Clin Oncol
1996;14:1730-1736.

Struewing
JP, Abeliovich D, Peretz T, et al: The carrier frequency
of the BRCA1 185delAG mutation is approximately
1 percent in Ashkenazi Jewish individuals. Nat
Genet 1995;11;198-200.

Struewing
JP, Hartge P, Wacholder S, et al. The risk of cancer
associated with specific mutations of BRCA1
and BRCA2 among Ashkenazi Jews. N
Engl J Med. 1997;336:1401-1408.

Streuwing
JP, Watson P, Easton DF, et al. Prophylactic oophorectomy
in inherited breast/ovarian cancer families. Monogr
Natl Cancer Inst 1994;17:33-35.

Tavtigian
SV, Simard J, Rommens J, et al. The complete BRCA2
gene and mutations in chromosome 13q-linked kindreds. Nat
Genet. 1996;12:333-337.

Thorlacius
S, et al. A single BRCA2
mutation in male and female breast cancer families from Iceland
with varied phenotypes. Nat Genet. 1996;13:117-119.

Tobacman
JK, Greene MH, Tucker MA, et al. Intra-abdominal carcinomatosis
after prophylactic oophorectomy in ovarian cancer-prone families.
Lancet. 1982;2:795-7.

Verhoog
LC, Brekelmans CTM, Seynaeve C, et al. Survival and
tumor characteristics of breast cancer patients with germline mutations
of BRCA1. Lancet.
1998;351:316-321.

Vogelstein
B, Knizler K. The Genetic Basis
of Human Cancer. McGraw Hill Companies. 1998;ISBN: 0-07-067596-1.

Wadler
J. Cancer Redyx: When I beat cancer.... (Story)
New York, September 15, 1997.

Whittemore
AS, Gong G, Itnyre J, et al. Prevalence and contribution
of BRCA1 mutations in breast cancer and
ovarian cancer: results from three U.S. population-based case-control
studies of ovarian cancer. Am J Hum Genet
1997;60:496-504.

Wooster
R, Bignell G, Lancaster J, et al. Identification of
the breast-cancer susceptibility gene BRCA2.
Nature 1995;378:789-792.

Wooster
R, Neuhausen SL, Mangio J, et al. Localization of
a breast cancer susceptibility gene, BRCA2,
to chromosome 13q12-13. Science. 1994;265:2088-2090.
* These articles are excellent overviews of their topic
matter. They are easy to read and provide important information
in a clear, concise manner.
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